Daily
Cape Girardeau
Friday, November 21st, 2025
Good morning, Cape Girardeau. Here's your local news at a glance for Friday, the 21st of November.
CULTURE NEWS
- ➤ Saint Francis Healthcare System will host its seventh annual outdoor Live Nativity on December 10 from 5 to 7 p.m. at the Cancer Institute Entrance 6—volunteers will portray biblical figures with live animals such as cows, camels, four-horn sheep, and a donkey—and parking is available nearby. Fox 23
EDUCATION NEWS
- ➤ Former SEMO professor Dr. Linda Heitman created a national online program on organ donation training that has reached over 5,000 nursing students. The program—funded by Mid-America Transplant and launched as a pilot in spring—includes five modules with quizzes, videos, interviews and discussion forums to prepare future nurses for their role in the donation process. Fox 23
HEALTH NEWS
- ➤ Missouri officials urged horse owners to quarantine and monitor their animals if they attended an event in Waco from November 5–9 or a barrel racing event in Guthrie, where Equine Herpes cases were found. They advised working with a veterinarian to check for signs of illness—no cases have been reported in Missouri. Fox 23
SPORTS NEWS
- ➤ The 2026 St. Louis Cardinals Caravan will stop at the Osage Community Center in Cape Girardeau on Monday, January 19 at 5:30 p.m.—offering free autographs, photo opportunities, and ticket giveaways for kids while the list of players and coaches has not yet been released. KFVS12
- ➤ Students & staff at Perry County School District 32 lined the campus Wednesday to send off the Perryville Pirates for their state semifinal match in Fenton; a break in the rain allowed a brief team parade & send-off before departure. Fox 23
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River Valley Craft Club – 50th Annual Craft Fair
River Valley Craft Club – 50th Annual Craft Fair – Multiple Crafters and Vendors with lots of handmade crafts and unique items, Santa will be joining us both days so bring your children to get a picture with Santa. Saturday and Sunday, November 22-23 at the A C Brase Arena Building, 410 Kiwanis Drive, Cape Girardeau, MO, event times are Saturday 9 am to 5 pm and Sunday 10 am to 4 pm.
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River Valley Craft Club – 50th Annual Craft Fair
River Valley Craft Club – 50th Annual Craft Fair – Multiple Crafters and Vendors with lots of handmade crafts and unique items, Santa will be joining us both days so bring your children to get a picture with Santa. Saturday and Sunday, November 22-23 at the A C Brase Arena Building, 410 Kiwanis Drive, Cape Girardeau, MO, event times are Saturday 9 am to 5 pm and Sunday 10 am to 4 pm.
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5th Annual Mary Mingle 5k
8 AM – 2 PM — Mary Jane bourbon + smokehouse — Registration required — Participate in a community-driven run and support a good cause.
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Toys For Tots 24-Hour Drive
8 AM-8 PM — Schnucks Cape Girardeau — Donations appreciated — Help make a child’s holiday brighter with toys and cash contributions for local families in need.
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Reveal the authorAbout Daily Cape Girardeau
Welcome to the Daily Cape Girardeau, your community newsletter that's anything but snooze-worthy, packed with positive, impactful local news + events across the Cape Girardeau, Missouri community. If you like the Daily Cape Girardeau, support us by subscribing to our email newsletter and sharing us with your friends and family in Cape Girardeau.
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